EBOO Therapy
Extracorporeal Blood Oxygenation and Ozonation
EBO2, or EBOO, is “extracorporeal blood oxygenation and ozonation.” It is a modern way of blood cleansing.
EBOO (also called EBO2) stands for Extracorporeal Blood Oxygenation and Ozonation — a sophisticated, clinically administered blood-cleansing therapy available at Biohackr Health’s San Francisco and Palo Alto locations.
Here’s how it works: blood is drawn from your body through an IV and circulated through a semi-permeable dialysis membrane infused with medical-grade ozone and Hemealumen light, a polychromatic, multi-wavelength phototherapy that simultaneously treats the blood as it flows through the circuit. Think of it as precision “ozone dialysis.” The oxygen-ozone mixture interacts with the blood as it flows through the membrane, filtering out excess fats, toxins, and inactive proteins. The cleansed, re-oxygenated blood then passes through the Hemealumen light therapy component — exposing it to therapeutic wavelengths of light — before returning to your body through a second IV in the opposite arm, completing the closed-loop circuit.The entire process takes approximately one hour.
Our providers have completed advanced training in EBOO therapy and have been performing this treatment for over five years across both clinic locations.
EBOO (aka EBO2) AT A GLANCE
Body EBO2
Best SellerWHAT:
EBOO (EBO2), or Extracorporeal Blood Oxygenation and Ozonation, is a clinically administered blood-cleansing therapy. This biohacking treatment can support patients dealing with fatigue, physical injuries, Lyme disease, long COVID, mold exposure, and inflammatory or autoimmune conditions — while also being used proactively for general wellness optimization, anti-inflammation, and athletic performance enhancement.
EBOO involves two IVs forming a closed-loop blood circuit with a medical-grade ozone filtration machine. The diffusing membranes filter excess fats, toxins, and inactive proteins from the blood before returning it to your system — refreshed and re-oxygenated.
TIME: Approximately one hour.
COST: $2,000
This is newer science. There are clear studies showing this top biohacking treatment helps with autoimmune, chronic inflammation, chronic diseases, and other issues.
HISTORY OF EBOO
The use of ozone in medicine is not new — researchers have been exploring different methods of blood ozonation for decades. While EBOO (EBO2) is not considered mainstream medicine, it is an active area of clinical study, particularly for conditions that conventional medicine has difficulty treating.
EBOO has been studied in the context of physical injuries, fatigue, Lyme disease, long COVID, mold exposure, and inflammatory or autoimmune conditions, as well as general wellness optimization and athletic performance support. Peer-reviewed research notes that “oxidation therapies have shown an extremely high safety profile… Ozone therapy, the most studied and least expensive to perform, is in itself a germicide.”
WHY DO EBO2?
Think of EBOO as a powerful filtration system for your blood. For those dealing with chronic disease, systemic inflammation, recurring infections, mold or environmental toxin exposure, and long-haul viral conditions, EBOO is thought to support the body’s natural detoxification and healing processes. Biohackr Health has been offering EBOO treatments in San Francisco and Palo Alto for over five years, and our providers have advanced training in this therapy.
Studied applications and benefits of blood ozonation include:
- Arterial circulatory disorders
- Chronic inflammatory processes – orthopedic, rheumatology, rheumatoid arthritis
- Lyme disease
- Long-Covid and viruses/bacterial diseases
- Diseases of the arteries, especially in diabetics
- Chronic intestinal disease
- Chronic hepatitis B and C
- Diseases related to aging
There are emerging studies in this space looking to see if it helps with Alzheimer’s and microplastics. See our blogs.
- Potential improvement in Alzheimer circulating amyloid beta
- Possibly removes microplastics- emerging studies

ABOUT BIOHACKR HEALTH
Biohackr Health is a leading Bay Area functional and regenerative medicine practice with locations in San Francisco and Palo Alto. Our board-certified physicians and trained practitioners specialize in longevity medicine, hormone optimization, and advanced therapies like EBOO — combining evidence-based protocols with a whole-body approach to wellness.
We’ve been performing EBOO treatments for over five years, and our providers hold advanced certifications in extracorporeal blood oxygenation and ozonation therapy. Every patient receives a personalized consultation before treatment to ensure EBOO is the right fit for their health goals.

Board Certification & Affiliations

Board-Certified by the American Board of Obstetrics and Gynecology

Diplomate, American Board of Plastic Surgery

American Society of Plastic Surgeons (ASPS)

Member, The Aesthetic Society (ASAPS)

Member, California Medical Association
HOW DOES EBOO (EBO2) WORK?
The mechanisms behind EBOO are multifaceted. Beyond the physical filtration of the blood, the ozonation process introduces therapeutic oxidation that is thought to benefit the body in several ways. Current research and clinical experience suggest EBOO may support:
- Reduction of oxidative stress
- Red blood cell metabolism and flexibility
- ATP production and mitochondrial function
- Increased oxygen delivery to tissues
- Activation of immunocompetent cells
- Modulation of interferons and interleukins (immune signaling molecules)
Individual results vary, and many patients report improvements in energy, mental clarity, circulation, sleep, breathing, and overall sense of wellness following treatment.
What Is Hemealumen (Polychromatic Light Therapy)?
Biohackr Health’s EBOO treatments incorporate Hemealumen therapy — a polychromatic, multi-wavelength phototherapy system built directly into the EBOO blood circuit. As your blood flows through the dialysis membrane, it is simultaneously exposed to multiple specific wavelengths of light, each targeting different biological mechanisms:
| Wavelength | Effect |
|---|---|
UVC (253.7 nm) |
Reduces residual viral particles and inflammatory cytokine activity |
UVA (340, 365 nm) |
Stimulates NAD+ production to support mitochondrial repair |
Violet (430 nm) |
Anti-inflammatory; enhances nitric oxide production and reduces oxidative stress |
Green (520 nm) |
Improves blood viscosity and microcirculation |
Red / Near-Infrared (630, 660, 810 nm) |
Increases ATP production, accelerates tissue repair, and modulates immune function |
This multi-wavelength delivery treats the blood across a broad therapeutic spectrum in a single session — simultaneously supporting immune activation, cellular energy, and circulation in a way that single-wavelength therapies cannot replicate. It is one of the key features that distinguishes Biohackr Health’s EBOO treatments from basic ozone therapy.
EBOO Patient Journey
Our “I Got Biohacked” series featuring Stevie follows her journey as she experiences for the first time our EBO2 (Extracorporeal Blood Oxygenation and Ozonation = EBOO) treatment at Biohackr Health.
EBOO Pricing at Biohackr Health
Option | Price |
|---|---|
Single EBOO Session | $2,000 |
3-Session Package | $1,800/session ($5,400 total) |
Each EBOO session is approximately one hour and involves two IVs forming a closed-loop circuit that oxygenates, ozonates, and filters the blood using medical-grade ozone.
How does EBOO compare to 10-pass ozonation?
If you’ve been researching ozone therapy in the Bay Area, you may have encountered “10-pass ozonation” (HBO3), which typically ranges from $1,500–$3,000 per session. We prefer EBOO (EBO2) because the science shows it delivers significantly more therapeutic ozone:
- High-dose 10-pass hyperbaric ozone (HBO3) delivers approximately 140,000 μg of ozone.
- EBOO (ozone dialysis at 30 μg/mL, 30 mL/min flow rate) delivers 460,000 μg — more than 3x the ozone of the 10-pass method.
To see the study, click HERE

Frequently Asked Questions
What is EBOO and how is it different from other ozone therapies?
EBOO — also called EBO2, or Extracorporeal Blood Oxygenation and Ozonation — is an advanced form of ozone therapy in which blood is removed from the body, filtered through a medical-grade dialysis membrane infused with ozone, and returned to the bloodstream cleansed and re-oxygenated. Unlike simpler ozone methods such as 10-pass ozonation, EBOO delivers more than three times the therapeutic ozone dose, making it one of the most potent ozone-based treatments available.
Is EBOO safe? What does it feel like?
Safety and comfort are the most common concerns patients bring to their first consultation — and we take both seriously. EBOO is performed using medically established ozone protocols with a closed-loop blood circuit, ensuring your blood never makes contact with the external environment. Most patients find the procedure comfortable; you'll have two IVs in place and can relax for the approximately one-hour treatment. Our providers follow rigorous safety protocols and conduct a full medical screening before any patient begins treatment.
How long has Biohackr Health been performing EBOO?
Biohackr Health has been performing EBOO treatments for over five years across both our San Francisco and Palo Alto locations. Our providers have completed advanced training and hold certifications in EBOO therapy, and this is one of our most established treatment offerings.
How much does EBOO cost at Biohackr Health?
A single EBOO session is $2,000. Patients who purchase a series of three sessions pay $1,800 per session ($5,400 total). A consultation is recommended before beginning treatment to ensure EBOO is appropriate for your health goals.
Who is a good candidate for EBOO?
Ideal candidates for EBOO are individuals looking to support overall wellness, energy, recovery, detoxification, circulation, immune health, and performance. Many patients seek EBOO as part of a proactive longevity or wellness strategy. EBOO is also commonly sought by patients dealing with hard to treat chronic issues, like long COVID, mold exposure, Lyme disease, autoimmune conditions, viral infections, and those recovering from chemotherapy. It is a tool to help treat conditions which are hard to treat.
Who is not a good candidate for EBOO?
EBOO may not be appropriate for everyone. Individuals with certain blood disorders, active bleeding conditions, severe anemia, uncontrolled cardiovascular instability, or other specific medical contraindications may not be eligible for treatment. A full consultation and medical screening is required before beginning EBOO to determine individual eligibility and safety.
What results do patients typically experience after EBOO?
Results vary from person to person, but patients commonly report improvements in energy levels, mental clarity, circulation, recovery, sleep, and overall sense of wellness. Many patients describe feeling refreshed and more balanced. Some patients have also noticed improvements in vision, breathing, and immune function following treatment. A series of sessions is often recommended for more sustained results.
What makes Biohackr Health's approach to EBOO different?
Rather than offering EBOO as a standalone trend treatment, Biohackr Health integrates it into a broader functional and regenerative health strategy. We evaluate each patient's goals, lifestyle, and overall health picture before recommending treatment, and our providers bring more than five years of hands-on EBOO experience across two Bay Area locations. Patient education and individualized care are central to how we approach every treatment.
READY TO EXPERIENCE EBOO IN SAN FRANCISCO OR PALO ALTO?
Biohackr Health has been offering EBOO therapy for over five years at our San Francisco and Palo Alto locations. Whether you’re managing a chronic condition or optimizing your health proactively, our team is here to help you determine if EBOO is right for you.
