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EBOO (aka EBO2) AT A GLANCE

HISTORY OF EBOO

The use of ozone in medicine is not new — researchers have been exploring different methods of blood ozonation for decades. While EBOO (EBO2) is not considered mainstream medicine, it is an active area of clinical study, particularly for conditions that conventional medicine has difficulty treating.

EBOO has been studied in the context of physical injuries, fatigue, Lyme disease, long COVID, mold exposure, and inflammatory or autoimmune conditions, as well as general wellness optimization and athletic performance support. Peer-reviewed research notes that “oxidation therapies have shown an extremely high safety profile… Ozone therapy, the most studied and least expensive to perform, is in itself a germicide.”

WHY DO EBO2?

Think of EBOO as a powerful filtration system for your blood. For those dealing with chronic disease, systemic inflammation, recurring infections, mold or environmental toxin exposure, and long-haul viral conditions, EBOO is thought to support the body’s natural detoxification and healing processes. Biohackr Health has been offering EBOO treatments in San Francisco and Palo Alto for over five years, and our providers have advanced training in this therapy.

Studied applications and benefits of blood ozonation include:

  • Arterial circulatory disorders
  • Chronic inflammatory processes – orthopedic, rheumatology, rheumatoid arthritis
  • Lyme disease
  • Long-Covid and viruses/bacterial diseases
  • Diseases of the arteries, especially in diabetics
  • Chronic intestinal disease
  • Chronic hepatitis B and C
  • Diseases related to aging

There are emerging studies in this space looking to see if it helps with Alzheimer’s and microplastics. See our blogs.

  • Potential improvement in Alzheimer circulating amyloid beta
  • Possibly removes microplastics- emerging studies

ABOUT BIOHACKR HEALTH

Biohackr Health is a leading Bay Area functional and regenerative medicine practice with locations in San Francisco and Palo Alto. Our board-certified physicians and trained practitioners specialize in longevity medicine, hormone optimization, and advanced therapies like EBOO — combining evidence-based protocols with a whole-body approach to wellness.

We’ve been performing EBOO treatments for over five years, and our providers hold advanced certifications in extracorporeal blood oxygenation and ozonation therapy. Every patient receives a personalized consultation before treatment to ensure EBOO is the right fit for their health goals.

Meet our Team

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Board Certification & Affiliations

HOW DOES EBOO (EBO2) WORK?

The mechanisms behind EBOO are multifaceted. Beyond the physical filtration of the blood, the ozonation process introduces therapeutic oxidation that is thought to benefit the body in several ways. Current research and clinical experience suggest EBOO may support:

Individual results vary, and many patients report improvements in energy, mental clarity, circulation, sleep, breathing, and overall sense of wellness following treatment.

What Is Hemealumen (Polychromatic Light Therapy)?

Biohackr Health’s EBOO treatments incorporate Hemealumen therapy — a polychromatic, multi-wavelength phototherapy system built directly into the EBOO blood circuit. As your blood flows through the dialysis membrane, it is simultaneously exposed to multiple specific wavelengths of light, each targeting different biological mechanisms:

Wavelength Effect
UVC (253.7 nm)
Reduces residual viral particles and inflammatory cytokine activity
UVA (340, 365 nm)
Stimulates NAD+ production to support mitochondrial repair
Violet (430 nm)
Anti-inflammatory; enhances nitric oxide production and reduces oxidative stress
Green (520 nm)
Improves blood viscosity and microcirculation
Red / Near-Infrared (630, 660, 810 nm)
Increases ATP production, accelerates tissue repair, and modulates immune function

This multi-wavelength delivery treats the blood across a broad therapeutic spectrum in a single session — simultaneously supporting immune activation, cellular energy, and circulation in a way that single-wavelength therapies cannot replicate. It is one of the key features that distinguishes Biohackr Health’s EBOO treatments from basic ozone therapy.

EBOO Patient Journey

Our “I Got Biohacked” series featuring Stevie follows her journey as she experiences for the first time our EBO2 (Extracorporeal Blood Oxygenation and Ozonation = EBOO) treatment at Biohackr Health.

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EBOO Pricing at Biohackr Health

Option

Price

Single EBOO Session

$2,000

3-Session Package

$1,800/session ($5,400 total)

Each EBOO session is approximately one hour and involves two IVs forming a closed-loop circuit that oxygenates, ozonates, and filters the blood using medical-grade ozone.

How does EBOO compare to 10-pass ozonation?

If you’ve been researching ozone therapy in the Bay Area, you may have encountered “10-pass ozonation” (HBO3), which typically ranges from $1,500–$3,000 per session. We prefer EBOO (EBO2) because the science shows it delivers significantly more therapeutic ozone:

  • High-dose 10-pass hyperbaric ozone (HBO3) delivers approximately 140,000 μg of ozone.
  • EBOO (ozone dialysis at 30 μg/mL, 30 mL/min flow rate) delivers 460,000 μg — more than 3x the ozone of the 10-pass method.

To see the study, click HERE

Frequently Asked Questions

READY TO EXPERIENCE EBOO IN SAN FRANCISCO OR PALO ALTO?

Biohackr Health has been offering EBOO therapy for over five years at our San Francisco and Palo Alto locations. Whether you’re managing a chronic condition or optimizing your health proactively, our team is here to help you determine if EBOO is right for you.

Schedule a Consultation

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The content on this page was co-authored and medically reviewed by the expert team of physicians at Biohackr Health, a leading San Francisco Bay Area practice specializing in longevity medicine, hormone optimization, and regenerative therapies. Our board-certified physicians include specialists in OB/GYN, plastic surgery, and anti-aging medicine, with advanced training and affiliations at leading academic medical centers and national recognition for clinical excellence, research, and patient care.


By leveraging more than 50 years of combined medical experience and a commitment to evidence-based protocols, our team strives to ensure all content reflects the most current and scientifically supported information in longevity medicine, hormone therapy, aesthetic rejuvenation, and whole-body optimization. Because this is a rapidly evolving field, some treatments discussed may be based on emerging research and should not be considered medical advice.

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