What is the buzz about peptides?
Peptides are short chains of amino acids (typically 2–50) linked together by peptide bonds. Oligopeptides are shorter 2-20 amino acids. Polypeptides are longer, 51 amino acids or longer, and can form proteins. Peptides are a super broad array of what they look like and what they are used for. They have use in
- Hormones, like insulin and glucagon to regulate blood sugar
- Neurotransmitters, acting as chemical messengers in t he brain
- Some have antimicrobial properties, helping fight bacteria
- Collagen and connective tissue- these peptides help with structure of the skin.
What is the peptide BPC-157?
BPC157 is a synthetic peptide made of 15 amino acids. It comes from a sequence found naturally in human gastric juice. This pentadecapeptide (pentadeca= 15) is sometimes called the “body protection compound,” as it was shown to help prevent ulcers and help wound healing. It has been used in studies looking at benefits in tissue injury, inflammatory bowel disease (like Ulcerative Colitis), central nervous system issues (like MS), and vascular healing.
Why is BPC-157 thought to help?
Studies show that it is stable in gastric juice (a harsh environment). It promotes formation of new blood vessels, protects skin and the cells that line blood vessels, and modulates the nitric oxide pathways. In English what does this mean? Animal studies have shown:
- Accelerated healing in GI tract, skin, muscle, nerve, and bone
- Protection against blood clots
- Protection against ischemia reperfusion injury (This is when an area doesn’t get blood flow, which the tissue needs to live. When blood flow is restored, it can cause injury when it comes back into the area).
- Neuroprotective effects (protects the nerves) and interacts with neurotransmitters
What studies have been done in humans?
There have been promising small trials in humans looking at ulcerative colitis and multiple sclerosis (MS). It is not approved by the FDA, and there is no official indication yet for it. The animal studies and early human trials though think it is safe, with no significant toxicity reported.
Is BPC-157 Offered at Biohackr Health?
We have clients who want BPC-157 to help
- heal faster from injury
- reduce inflammation
- reduce pain
- improve tissue repair, especially for muscles, tendons, and ligaments
- it may help gut health
This is the essence of biohacking. We are continuously researching emerging treatments which can help people. We like to see science backing of use and safety. BPC-157 has both of those. It was temporarily banned by WADA in 2022 but is not currently listed as prohibited.
Medical Citations
- Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review.Pharmaceuticals (Basel, Switzerland). 2025
- Stable Gastric Pentadecapeptide BPC 157 and Wound Healing. Frontiers in Pharmacology. 2021
- Fistulas Healing. Stable Gastric Pentadecapeptide BPC 157 Therapy.Current Pharmaceutical Design. 2020;
- Novel Cytoprotective Mediator, Stable Gastric Pentadecapeptide BPC 157. Vascular Recruitment and Gastrointestinal Tract Healing. Pharmaceutical Design. 2018
- Cytoprotective Gastric Pentadecapeptide BPC 157 Resolves Major Vessel Occlusion Disturbances, Ischemia-Reperfusion Injury Following Pringle Maneuver, and Budd-Chiari Syndrome. World Journal of Gastroenterology. 2022
- Focus on Ulcerative Colitis: Stable Gastric Pentadecapeptide BPC 157. Current Medicinal Chemistry. 2012
- Stable Gastric Pentadecapeptide BPC 157: Novel Therapy in Gastrointestinal Tract. Current Pharmaceutical Design. 2011
- Brain-Gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Current Neuropharmacology. 2016
- Stress in Gastrointestinal Tract and Stable Gastric Pentadecapeptide BPC 157. Finally, Do We Have a Solution?.Current Pharmaceutical Design. 2017